Medicines that don't mix well with extreme heat: What to know
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LOS ANGELES - As millions of Americans continue to be impacted by a sweltering heat wave in many parts of the country, illness threatened by the extreme weather isn't the only concern.
Heat can amplify the side effects of many common medications, damage medicines like insulin, cause inhalers to explode, and cause EpiPens to malfunction. Even mail-order medications can deteriorate.
Here's everything you should know about how heat impacts medicine:
Medicines affected by heat
Blood pressure pills that reduce fluid in the blood can lead to dehydration. Beta-blockers can reduce blood flow to the skin, making you less aware of dangerous heat. Some antidepressants hinder cooling, and pain relievers like aspirin decrease fluid and sodium levels.
Combining heat with drug side effects can cause lightheadedness and falls. Alcohol increases this danger, said Bradley Phillips of the University of Florida College of Pharmacy. Learn more about your medications at MedlinePlus or talk to your doctor or pharmacist about hydration.
Some medicines, like antibiotics and acne drugs, can heighten sun sensitivity, causing rashes and sunburns. Dr. Mike Ren of Baylor College of Medicine advises using sun-protective fabrics and sunscreen.
Storing medications for travel
Medications should generally be kept in a cool, dry place unless refrigerated. Before a trip, check labels for storage requirements. Carry medicine in a cooler when traveling by car. In a plane, keep medication in your carry-on bag as checked luggage can get too cold.
Mail-order prescription concerns
Mail-order pharmacies must keep drugs at safe temperatures during storage and transit. Sensitive medicines should be shipped with ice packs and temperature monitors. If you receive a delivery during extreme heat and suspect damage, call the pharmacy to report it.
Research gaps in medicine and heat
Some common warnings about heat and drugs lack scientific evidence. Ollie Jay of the University of Sydney found support for only four of the 11 medication categories listed by the World Health Organization. He suggested to the Associated Press changing behavior, like staying out of the heat, rather than medication.
Dr. Renee Salas of Massachusetts General Hospital added that as climate change accelerates, it is necessary to identify which medicines are riskiest in the heat.
The Associated Press contributed to this story.